Anti-TTR Polyclonal Antibody
This product is not available outside of the U.S.
| Host / Isotype: |
Chicken |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Human (Hu) |
| Immunogen: |
TTR fusion protein. |
|
| Immunohistochemistry (IHC) |
1:200 |
| Western Blot (WB) |
1:3,000 |
| Pierce Anti-TTR Polyclonal Antibody |
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| Product Number |
Pkg Size |
Price |
|
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| PY-10237 |
100 µg |
$285.00 |
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 µg of affinity purified antibody in PBS buffer in lyophilized powder. Redissolving the powder with 100µL sterile water will restore the original concentration to 1mg/mL. |
PY-10237 detects TTR in human samples.
PY-10237 has been successfully used in Western blot and immunohistochemistry procedures.
The PY-10237 immunogen is TTR corresponding to residues 20-68) fusion protein.
Figure 1 illustrates immunohistochemical staining of TTR in oral cancer epithelium using PY-10237 and the AEC method. |
Transthyretin(TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition. |
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No references for this product. |
This product is for In Vitro experimental use only
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