| Details | |
| Host / Isotype: | Chicken |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Human CD105 fusion protein. |
| Ordering Information | ||||
| Pierce Anti-CD105 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PY-10183 | 100 µg | $314.00 | ||
This product is not available outside of the U.S.
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in PBS buffer in lyophilized powder. Redissolving the powder with 100µL sterile water will restore the original concentration to 1mg/mL. |
| Applications | Dilution |
| Western Blot (WB) | 1:500 |
| Product Specific Information |
| PY-10183 detects CD105 in human samples. PY-10183 has been successfully used in Western blot procedures. The PY-10183 immunogen is a human CD105 fusion protein corresponding to residues 341-470. |
| General Information |
| CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. |
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PO
Box 117, Rockford, IL 61105 USA |
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