Anti-MMP12 Polyclonal Antibody
This product is not available outside of the U.S.
| Host / Isotype: |
Chicken |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
|
| Label: |
|
| Species Reactivity: |
Human (Hu) |
| Immunogen: |
Human MMP12 fusion protein. |
|
| Pierce Anti-MMP12 Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| PY-10169 |
100 µg |
$342.00 |
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 µg of affinity purified antibody in PBS buffer in lyophilized powder. Redissolving the powder with 100µL sterile water will restore the original concentration to 1mg/mL. |
PY-10169 detects MMP12 in human samples.
PY-10169 has been successfully used in Western blot procedures.
The PY-10169 immunogen is a human MMP12 fusion protein corresponding to residues 35-117. |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive pr-proteins which are activated when cleaved by extracellular proteinases. It is thought that this protein is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. |
No references for this product. |
This product is for In Vitro experimental use only
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