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Anti-Cytokeratin 18 Polyclonal Antibody

Synonyms:
CK-18, Keratin-18, K18, Cytokeratin endo B, Keratin D
Entrez Gene ID:
(Human) 3875, (Murine) 16668, (Rat) 294853
UniProt ID:
P05783
Details
Host / Isotype: Chicken
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: KRT8 fusion protein.
Ordering Information
Pierce Anti-Cytokeratin 18 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PY-10150 100 µg $314.00

This product is not available outside of the U.S.



Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of affinity purified antibody in PBS buffer in lyophilized powder. Redissolving the powder with 100µL sterile water will restore the original concentration to 1mg/mL.


Applications Dilution
Western Blot (WB) 1:500
Product Specific Information
PY-10150 detects Cytokeratin 18 in human, mouse and rat samples.

PY-10150 has been successfully used in Western blot procedures.

The PY-10150 immunogen is a KRT8 fusion protein corresponding to residues 391-483.
General Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
(This product is for In Vitro experimental use only.)


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