| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein. |
| Ordering Information | ||||
| Pierce Anti-Gastrin-Releasing Peptide Receptor Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA3-304 | 100 µl | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µL of antisera containing 0.05% sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/ml |
| Western Blot (WB) | 1 µg/ml |
| Product Specific Information |
| PA3-304 detects GRP-R/ BB2 in human samples. PA3-304 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects a broad ~65 kDa band representing the various glycosylated forms of GRP-R. The PA3-304 immunogen is a synthetic peptide corresponding to residues T(364) N P S V A T F S L I N G N I C H E R Y V(384) of human GRP-R receptor protein. Figure 1 illustrates immunohistochemical staining of GRPR in paraffin embedded human mammary carcinoma tissue sections using PA3-304. |
| General Information |
| Gastrin-releasing peptide-preferring bombesin receptor is often detected in prostate and breast carcinomas. These are confined to the plasma membrane and uniformly present on nearly all tumor cells. These anti-peptide antibodies will facilitate identification of these tumors. |
| References: |
| Virchows Archiv, 449: 421-427, 2006 |
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