| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | A synthetic peptide within the extreme C-terminus of the human BACH1/Brip1 protein sequence. |
| Ordering Information | ||||
| Pierce Anti-BRIP1 / FANCJ Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA3-16591 | 100 µl | $285.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl of whole rabbit antisera with 0.01% Sodium Azide. |
| Applications | Dilution |
| ChIP assay (ChIP) | Assay Dependent |
| Immunoprecipitation (IP) | 2 ul |
| Western Blot (WB) | 1:2000 |
| Product Specific Information |
| PA3-16591 detects BRIP1 / FANCJ in Human samples. PA3-16591 has successfully been used in Western Blot, Immunoprecipitation and Chromatin Immunoprecipitaion applications. The BRIP1 / FANCJ molecular weight is 130 kDa. The PA3-16591 immunizing agent corresponds to the C-terminal sequence of human BACH1. |
| General Information |
| BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation. |
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