Anti-Lubricin Polyclonal Antibody
Printable Datasheet
Synonyms:
Proteoglycan-4, Megakaryocyte stimulating factor, Superficial zone proteoglycan, PRG4
Entrez Gene ID:
(Human) 10216
UniProt ID:
Q92954
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin. |
| Ordering Information | ||||
| Pierce Anti-Lubricin Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA3-130 | 100 µg | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ug of affinity purified antibody (1mg/ml) in PBS containing 1mg/ml BSA and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1 µg/ml |
| Product Specific Information |
| PA3-130 detects lubricin in human samples. PA3-130 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~64 kDa protein representing lubricin in human samples. The PA3-130 immunogen is a synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin. This polyclonal antibody has been referred to as: JSCIQQ. This peptide (Cat. # PEP-288) is available for use in neutralization and control experiments. Figure 1 illustrates Western blot detection of human recombinant lubricin using PA3-130. |
| General Information |
| Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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