Anti-Lubricin Polyclonal Antibody
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Human (Hu) |
| Immunogen: |
Synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin. |
|
| Western Blot (WB) |
1 µg/ml |
| Pierce Anti-Lubricin Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| PA3-130 |
100 µg |
$354.00 |
|
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 ug of affinity purified antibody (1mg/ml) in PBS containing 1mg/ml BSA and 0.05% sodium azide. |
PA3-130 detects lubricin in human samples.
PA3-130 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~64 kDa protein representing lubricin in human samples.
The PA3-130 immunogen is a synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin. This polyclonal antibody has been referred to as: JSCIQQ. This peptide (Cat. # PEP-288) is available for use in neutralization and control experiments.
Figure 1 illustrates Western blot detection of human recombinant lubricin using PA3-130. |
Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder. |
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No references for this product. |
This product is for In Vitro experimental use only
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