Anti-PAC1 Polyclonal Antibody
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Synonyms:
Pituitary Adenylate Cyclase-activating peptide receptor,
Entrez Gene ID:
(Human) 117
UniProt ID:
P41586
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human PAC1. |
| Ordering Information | ||||
| Pierce Anti-PAC1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA3-115 | 100 µl | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ul of antiserum containing 0.05% sodium azide. |
| Applications | Dilution |
| Immunocytochemistry (ICC) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Western Blot (WB) | 1:1,000 |
| Product Specific Information |
| PA3-115 detects PAC1 in human samples. PA3-115 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40-60 kDa protein representing PAC1 in human samples. In immunohistochemistry, PAC1 immunoreactivity is predominantly localized to the plasma membrane. PA3-115 immunogen is a synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human VPAC2 receptor. Figure 1 shows Immunohistochemical staining of PAC1 in human myenteric ganglia cells of the small intestine using PA3-115. |
| General Information |
| The pituitary adenylate cyclase-activating peptide receptor (PAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. PAC1 demonstrates a higher affinity for PACAP than VIP. Expression of the VIP and VACAP receptors has been linked to the presence of human tumors. |
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Immunohistochemistry with anti-PAC1 Polyclonal Antibody (PA3-115)
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(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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