Anti-PAC1 Polyclonal Antibody
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Human (Hu) |
| Immunogen: |
Synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human PAC1. |
|
| Immunocytochemistry (ICC) |
1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) |
1:500 |
| Western Blot (WB) |
1:1,000 |
| Pierce Anti-PAC1 Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| PA3-115 |
100 µl |
$354.00 |
|
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 ul of antiserum containing 0.05% sodium azide. |
PA3-115 detects PAC1 in human samples.
PA3-115 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40-60 kDa protein representing PAC1 in human samples. In immunohistochemistry, PAC1 immunoreactivity is predominantly localized to the plasma membrane.
PA3-115 immunogen is a synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human VPAC2 receptor.
Figure 1 shows Immunohistochemical staining of PAC1 in human myenteric ganglia cells of the small intestine using PA3-115. |
The pituitary adenylate cyclase-activating peptide receptor (PAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. PAC1 demonstrates a higher affinity for PACAP than VIP. Expression of the VIP and VACAP receptors has been linked to the presence of human tumors. |
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This product is for In Vitro experimental use only
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