| Details | |
| Host / Isotype: | Chicken / IgY |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) Rabbit (Rb) Bovine (Bv) |
| Immunogen: | Recombinant, His-tagged VDAC3 protein expressed in E. coli. |
| Ordering Information | ||||
| Pierce Anti-VDAC3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-959 | 100 µg | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ug of affinity purified IgY antibody in PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | Assay dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay dependent |
| Western Blot (WB) | 1:500 |
| Product Specific Information |
| PA1-959 detects VDAC3 in mouse, human, rat, rabbit and bovine samples. PA1-959 has been used successfully in Western blot, ELISA, and immunohistochemistry (paraffin) procedures. By Western blot PA1-959 is specific for the ~30 kDa VDAC3 protein. The PA1-959 immunogen is recombinant, His-tagged VDAC3 protein expressed in E. coli. Figure 1 illustrates Western blot detection of recombinant VDAC3 protein purified from E. coli using PA1-959. |
| General Information |
| The Voltage-Dependant Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane. |
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