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Anti-VDAC3 Polyclonal Antibody

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Details
Host / Isotype: Chicken / IgY
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt) Rabbit (Rb) Bovine (Bv)
Immunogen: Recombinant, His-tagged VDAC3 protein expressed in E. coli.
Applications Dilution
ELISA (ELISA) Assay dependent
Immunohistochemistry (Paraffin) (IHC (P)) Assay dependent
Western Blot (WB) 1:500
Ordering Information
Pierce Anti-VDAC3 Polyclonal Antibody
Product Number Pkg Size Price


PA1-959 100 µg $354.00
Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of affinity purified IgY antibody in PBS containing 1 mg/ml BSA and 0.05% sodium azide.


Product Specific Information General Information
PA1-959 detects VDAC3 in mouse, human, rat, rabbit and bovine samples.

PA1-959 has been used successfully in Western blot, ELISA, and immunohistochemistry (paraffin) procedures. By Western blot PA1-959 is specific for the ~30 kDa VDAC3 protein.

The PA1-959 immunogen is recombinant, His-tagged VDAC3 protein expressed in E. coli.

Figure 1 illustrates Western blot detection of recombinant VDAC3 protein purified from E. coli using PA1-959.
The Voltage-Dependant Anion Channel (VDAC) of the outer mitochondrial membrane, a small abundant protein found in all eukaryotic kingdoms, forms a voltage-gated pore when incorporated into planar lipid bilayers. VDAC is also the site of binding of the metabolic enzymes hexokinase and glycerol kinase to the mitochondrion in what may be a significant metabolic regulatory interaction. VDAC3 is involved specifically in translocation of adenine nucleotides through the outer membrane.
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References:
Arch Biochem Biophys; 2004. 422(2): 191-196.
Mol. Gen.,Meta. 2000. 70:69-74.
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