| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the C terminus amino acids EFTKKYGEKRPVD. |
| Ordering Information | ||||
| Pierce Anti-UBE2L3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9112 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 0.5-2 µg/ml |
| Product Specific Information |
| PA1-9112 detects UBE2L3 in human samples. PA1-9112 has been successfully used in Western blot procedures. PA1-9112 immunogen is a synthetic peptide corresponding to the C terminus of UBE2L3, amino acids EFTKKYGEKRPVD. Figure 1 illustrates Western blot detection of UBE2L3 in hela lysate using PA1-9112. |
| General Information |
| The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. |
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