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Anti-UBE2L3 Polyclonal Antibody

Synonyms:
UBE2L3; ubiquitin-conjugating enzyme E2L 3; UBCH7
Entrez Gene ID:
(Human) 7332
UniProt ID:
P68036
Details
Host / Isotype: Goat
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to the C terminus amino acids EFTKKYGEKRPVD.
Ordering Information
Pierce Anti-UBE2L3 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-9112 100 ug $268.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.


Applications Dilution
Western Blot (WB ) 0.5-2 µg/ml
Product Specific Information
PA1-9112 detects UBE2L3 in human samples.

PA1-9112 has been successfully used in Western blot procedures.

PA1-9112 immunogen is a synthetic peptide corresponding to the C terminus of UBE2L3, amino acids EFTKKYGEKRPVD.

Figure 1 illustrates Western blot detection of UBE2L3 in hela lysate using PA1-9112.
General Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
(This product is for In Vitro experimental use only.)


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