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Anti-MYD88 Polyclonal Antibody

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Synonyms:
MYD88; myeloid differentiation primary response gene (88)
Entrez Gene ID:
(Human) 4615
UniProt ID:
Q99836
Details
Host / Isotype: Goat
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Internal sequence corresponding to amino acids C-IKYKAMKKEFP.
Ordering Information
Pierce Anti-MYD88 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-9072 100 ug $268.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.


Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 2-5 µg/ml
Western Blot (WB ) 0.01-0.03 µg/ml
Product Specific Information
PA1-9072 detects MYD88 in human samples.

PA1-9072 has been successfully used in Western blot and immunohistochemistry (paraffin-embedded sections) procedures.

PA1-9072 immunogen is an internal sequence of the MYD88 protein corresponding to amino acids C-IKYKAMKKEFP.

Figure 1 illustrates Western blot detection of MYD88 in MOLT4 lysate using PA1-9072.

Figure 2 illustrates specific staining of paraffin embedded human tonsil using PA1-9072.
General Information
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Western Blot with anti-MYD88 Polyclonal Antibody (PA1-9072)
(This product is for In Vitro experimental use only.)


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