Anti-MYD88 Polyclonal Antibody
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Synonyms:
MYD88; myeloid differentiation primary response gene (88)
Entrez Gene ID:
(Human) 4615
UniProt ID:
Q99836
| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Internal sequence corresponding to amino acids C-IKYKAMKKEFP. |
| Ordering Information | ||||
| Pierce Anti-MYD88 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9072 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2-5 µg/ml |
| Western Blot (WB ) | 0.01-0.03 µg/ml |
| Product Specific Information |
| PA1-9072 detects MYD88 in human samples. PA1-9072 has been successfully used in Western blot and immunohistochemistry (paraffin-embedded sections) procedures. PA1-9072 immunogen is an internal sequence of the MYD88 protein corresponding to amino acids C-IKYKAMKKEFP. Figure 1 illustrates Western blot detection of MYD88 in MOLT4 lysate using PA1-9072. Figure 2 illustrates specific staining of paraffin embedded human tonsil using PA1-9072. |
| General Information |
| This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. |
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Western Blot with anti-MYD88 Polyclonal Antibody (PA1-9072)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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