| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the C terminus amino acids QRKQGAGAPTAP. |
| Ordering Information | ||||
| Pierce Anti-ADAM8 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9070 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 1-3 µg/ml |
| Product Specific Information |
| PA1-9070 detects ADAM8 in human samples. PA1-9070 has been successfully used in Western blot procedures. PA1-9070 immunogen is a synthetic peptide corresponding to the C terminus of ADAM8, amino acids QRKQGAGAPTAP. Figure 1 illustrates Western blot detection of ADAM8 in human brain lysate using PA1-9070. |
| General Information |
| This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. |
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