Anti-LAT Polyclonal Antibody
Printable Datasheet
Synonyms:
LAT; linker for activation of T cells; LAT1; pp36; 36 kDa phospho-tyrosine adaptor protein
Entrez Gene ID:
(Human) 27040
UniProt ID:
O43561
| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the C terminus amino acids GAPDYENLQELN. |
| Ordering Information | ||||
| Pierce Anti-LAT Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9063 | 100 ug | $322.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 1-3 µg/ml |
| Product Specific Information |
| PA1-9063 detects LAT in human samples. PA1-9063 has been successfully used in Western blot procedures. PA1-9063 immunogen is a synthetic peptide corresponding to the C terminus of LAT, amino acids GAPDYENLQELN. Figure 1 illustrates Western blot detection of LAT in human PBMC lysate using PA1-9063. |
| General Information |
| The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
(This product is for In Vitro experimental use only.)
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