Anti-ILK Polyclonal Antibody
Printable Datasheet
Synonyms:
ILK; integrin-linked kinase; P59
Entrez Gene ID:
(Human) 3611
UniProt ID:
Q13418
| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the C terminus amino acids DMIVPILEKMQDK. |
| Ordering Information | ||||
| Pierce Anti-ILK Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9056 | 100 ug | $322.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody (0.5 mg/ml) in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Western Blot (WB ) | 0.5-2 µg/ml |
| Product Specific Information |
| PA1-9056 detects ILK in human samples. Antibody is expected to react with mouse, rat and guinea pig samples based on sequence similarity. PA1-9056 has been successfully used in Western blot and peptide ELISA procedures. PA1-9056 immunogen is a synthetic peptide corresponding to the C terminus of ILK, amino acids DMIVPILEKMQDK (NP_004508.1; NP_001014794.1; NP_001014795.1). Figure 1 illustrates Western blot detection of ILK in A431 lysate using PA1-9056. |
| General Information |
| Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
(This product is for In Vitro experimental use only.)
 |
|||||||||||||
PO
Box 117, Rockford, IL 61105 USA |
 |
 |
