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Anti-ILK Polyclonal Antibody

Synonyms:
ILK; integrin-linked kinase; P59
Entrez Gene ID:
(Human) 3611
UniProt ID:
Q13418
Details
Host / Isotype: Goat
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to the C terminus amino acids DMIVPILEKMQDK.
Ordering Information
Pierce Anti-ILK Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-9056 100 ug $322.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of affinity purified antibody (0.5 mg/ml) in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.


Applications Dilution
ELISA (ELISA) Assay Dependent
Western Blot (WB ) 0.5-2 µg/ml
Product Specific Information
PA1-9056 detects ILK in human samples. Antibody is expected to react with mouse, rat and guinea pig samples based on sequence similarity.

PA1-9056 has been successfully used in Western blot and peptide ELISA procedures.

PA1-9056 immunogen is a synthetic peptide corresponding to the C terminus of ILK, amino acids DMIVPILEKMQDK (NP_004508.1; NP_001014794.1; NP_001014795.1).

Figure 1 illustrates Western blot detection of ILK in A431 lysate using PA1-9056.
General Information
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
(This product is for In Vitro experimental use only.)


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