| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the C terminus amino acids KIFDPQNPDENE. |
| Ordering Information | ||||
| Pierce Anti-CRKL Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9033 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 0.01-0.03 µg/ml |
| Product Specific Information |
| PA1-9033 detects CRKL in human samples. PA1-9033 has been successfully used in Western blot procedures. PA1-9033 immunogen is a synthetic peptide corresponding to the C terminus of CRKL, amino acids KIFDPQNPDENE. Figure 1 illustrates Western blot detection of CRKL in K562 lysate using PA1-9033. |
| General Information |
| This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
|
|||||||||||||
PO
Box 117, Rockford, IL 61105 USA |
|