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Anti-Choline Acetyltransferase Polyclonal Antibody

Synonyms:
CMS1A, CMS1A2, choline acetyltransferase, acetyl CoA, choline O-acetyltransferase
Entrez Gene ID:
(Human) 1103
UniProt ID:
P28329
Details
Host / Isotype: Goat
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to the C terminus amino acids CKEKATRPSQGHQP.
Ordering Information
Pierce Anti-Choline Acetyltransferase Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-9027 100 ug $268.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of affinity purified antibody (0.5 mg/ml) in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.


Applications Dilution
ELISA (ELISA) 1:32000
Western Blot (WB ) 0.03-0.3 µg/ml
Product Specific Information
PA1-9027 detects CHAT in human samples. Human, canine, and porcine samples are expected to cross react due to sequence similarity.

PA1-9027 has been successfully used in Western blot procedures. In Western blot an ~70kDa band is observed in human placenta lysates.

PA1-9027 immunogen is a synthetic peptide corresponding to the C terminus of CHAT, amino acids CKEKATRPSQGHQP.

Figure 1 illustrates Western blot detection of ChAT in human Placenta lysate using PA1-9027.
General Information
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
(This product is for In Vitro experimental use only.)


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