Anti-BAK Polyclonal Antibody
Printable Datasheet
Synonyms:
BAK1; BCL2-antagonist/killer 1; BAK; CDN1; BCL2L7; cell death inhibitor 1; apoptosis regulator BAK; Bcl-2 homologous antagonist/killer
Entrez Gene ID:
(Human) 578
UniProt ID:
Q16611
| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to the N terminus amino acids ASGQGPGPPRQE. |
| Ordering Information | ||||
| Pierce Anti-BAK Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9014 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 0.5-1 µg/ml |
| Product Specific Information |
| PA1-9014 detects BAK1 in human samples. PA1-9014 has been successfully used in Western blot procedures. PA1-9014 immunogen is a synthetic peptide corresponding to the N terminus of BAK1, amino acids ASGQGPGPPRQE. Figure 1 illustrates Western blot detection of BAK1 in A431 lysate using PA1-9014. |
| General Information |
| The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
(This product is for In Vitro experimental use only.)
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