| Details | |
| Host / Isotype: | Goat |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Internal sequence corresponding to amino acids CSPTSQIDNIGEEEM. |
| Ordering Information | ||||
| Pierce Anti-AKT3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-9004 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of affinity purified antibody in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Applications | Dilution |
| Western Blot (WB ) | 1-3 µg/ml |
| Product Specific Information |
| PA1-9004 detects AKT3 in human samples. PA1-9004 has been successfully used in Western blot procedures. PA1-9004 immunogen is an internal sequence of the AKT3 protein corresponding to amino acids CSPTSQIDNIGEEEM. Figure 1 illustrates Western blot detection of AKT3 in hepG2 lysate using PA1-9004. |
| General Information |
| The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. |
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