Anti-TIMP1 Polyclonal Antibody
Printable Datasheet
Synonyms:
RP1-230G1.3, CLGI, EPA, EPO, FLJ90373, HCI, TIMP
Entrez Gene ID:
(Human) 7076
UniProt ID:
P01033
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Rat (Rt) Rabbit (Rb) Bovine (Bv) Ovine (Ov) Equine (Eq) |
| Immunogen: | Human tissue inhibitor of metalloproteinase 1 (TIMP-1). |
| Ordering Information | ||||
| Pierce Anti-TIMP1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-85923 | 100 µg | $1,045.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg purified IgG (1 mg/ml) in phosphate buffered saline. Contains 0.02% Sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | 2.5-10 µg/ml |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1-5 µg/ml |
| Western Blot (WB) | 5-10 µg/ml |
| Product Specific Information |
| PA1-85923 detects native and denatured TIMP-1 in human, rabbit, ovine, ferret, bovine, rat and equine samples. This antibody also detects TIMP-1 in and out of enzyme/inhibitor complex. PA1-85923 has been successfully used in immunohistochemistry (paraffin), Western blot and ELISA applications. This antibody does not neutralize the protein activity. The immunogen used to produce PA1-85923 is from human tissue inhibitor of metalloproteinase 1 (TIMP-1). |
| General Information |
| This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
(This product is for In Vitro experimental use only.)
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