| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Fish (Fs) |
| Immunogen: | highly purified acetylcholine esterase from Electrophorus electricus. |
| Ordering Information | ||||
| Pierce Anti-Acetylcholinesterase Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-85113 | 1 ml | $231.00 | ||
| Storage: | -20ยบ C, Avoid Freeze/Thaw Cycles |
| Form: | 1 ml (5.0 mg/ml) antibody in PBS buffer. Contains 0.09% Sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | 1/6000 - 1/24k |
| Western Blot (WB) | 1/10 - 1/50 |
| Product Specific Information |
| PA1-85113 detects Acetylcholinesterase, Electric Eel in fish and human samples. PA1-85113 has been successfully used in Western blot and ELISA applications. The immunogen used to produce PA1-85113 is from highly purified acetylcholine esterase from Electrophorus electricus. |
| General Information |
| This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. |
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Box 117, Rockford, IL 61105 USA |
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