| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide. |
| Ordering Information | ||||
| Pierce Anti-SRC3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-84862 | 50 µg | $315.00 | ||
| Storage: | 4º C |
| Form: | 50 µg antibody (1 mg/ml) in Tris-citrate/phosphate buffer pH 7-8, with 0.09% Sodium azide. |
| Applications | Dilution |
| Immunoprecipitation (IP) | 1-4 µg/mg protein |
| Product Specific Information |
| PA1-84862 detects SRC3 in human samples. PA1-84862 has been successfully used in immunoprecipitation applications. The immunogen used to produce PA1-84862 is from a synthetic peptide corresponding to a region within human SRC3 encoded by exon 16. Store at 4ºC or -20ºC if preferred. |
| General Information |
| The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. |
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