| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to a region of human BARD1 encoded within exon 4. |
| Ordering Information | ||||
| Pierce Anti-BARD1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-84781 | 50 µg | $315.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µg antibody (1 mg/ml) in Tris-citrate/phosphate with 0.09% Sodium azide. |
| Applications | Dilution |
| Immunoprecipitation (IP) | 10 - 40 ug/mg protein |
| Western Blot (WB) | 1:1000 - 1:10,000 |
| Product Specific Information |
| PA1-84781 detects BARD1 in human samples. PA1-84781 has been successfully used in Western blot and immunoprecipitation applications. The immunogen used to produce PA1-84781 is from a synthetic peptide corresponding to a region of human BARD1 encoded within exon 4. |
| General Information |
| PA1-84781 is specific for human BARD1 (BRCA1 associated Ring Domain 1). BARD1 possesses an N-terminal RING motif and the C-terminal BRCT domain. As the name suggests, this protein is the major cellular binding protein of BRCA1. BARD1 is thought to play a key role in regulating BRCA1 stability, localisation and function. BARD1 is also reported to function as a tumour suppressor, since mutations in this protein have been implicated in a number of breast and ovarian cancers. |
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