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Anti-BARD1 Polyclonal Antibody

Entrez Gene ID:
(Human) 580
UniProt ID:
Q99728
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to a region of human BARD1 encoded within exon 4.
Ordering Information
Pierce Anti-BARD1 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-84781 50 µg $315.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 50 µg antibody (1 mg/ml) in Tris-citrate/phosphate with 0.09% Sodium azide.


Applications Dilution
Immunoprecipitation (IP) 10 - 40 ug/mg protein
Western Blot (WB) 1:1000 - 1:10,000
Product Specific Information
PA1-84781 detects BARD1 in human samples.

PA1-84781 has been successfully used in Western blot and immunoprecipitation applications.

The immunogen used to produce PA1-84781 is from a synthetic peptide corresponding to a region of human BARD1 encoded within exon 4.
General Information
PA1-84781 is specific for human BARD1 (BRCA1 associated Ring Domain 1).

BARD1 possesses an N-terminal RING motif and the C-terminal BRCT domain. As the name suggests, this protein is the major cellular binding protein of BRCA1. BARD1 is thought to play a key role in regulating BRCA1 stability, localisation and function.

BARD1 is also reported to function as a tumour suppressor, since mutations in this protein have been implicated in a number of breast and ovarian cancers.
(This product is for In Vitro experimental use only.)


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