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CYTOCHROME P450 2E1 ANTIBODIES > CYTOCHROME P450 2E1 POLYCLONAL ANTIBODY PA1-84226
Anti-Cytochrome P450 2E1 Polyclonal Antibody
Printable Datasheet
Synonyms:
CPE1, CYP2E, P450-J, P450C2E
Entrez Gene ID:
(Human) 1571
UniProt ID:
P05181
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Purified human CYP2E1 expressed in E.Coli. |
| Ordering Information | ||||
| Pierce Anti-Cytochrome P450 2E1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-84226 | 50 µl | $463.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µl serum. |
| Applications | Dilution |
| Functional Assay (FN) | 2-20 µl |
| Product Specific Information |
| PA1-84226 detects Cytochrome P450 2E1 in human samples. PA1-84226 has been successfully used in Functional assay applications. The immunogen used to produce PA1-84226 is from purified human CYP2E1 expressed in E.Coli. |
| General Information |
| This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. |
(This product is for In Vitro experimental use only.)
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