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AMYLOID PRECURSOR PROTEIN ANTIBODIES > AMYLOID PRECURSOR PROTEIN POLYCLONAL ANTIBODY PA1-84111
Anti-Amyloid Precursor Protein Polyclonal Antibody
Printable Datasheet
Synonyms:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
Entrez Gene ID:
(Human) 351
UniProt ID:
P05067
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Non-human primate (Nhp) |
| Immunogen: | Proprietary Immunogen. |
| Ordering Information | ||||
| Pierce Anti-Amyloid Precursor Protein Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-84111 | 100 µl | $347.00 | ||
| Storage: | 4º C |
| Form: | 100 µl Serum - liquid. Contains 0.02% Sodium azide. |
| Applications | Dilution |
| Immunoprecipitation (IP) | Assay Dependent |
| Western Blot (WB) | 1/500 |
| Product Specific Information |
| PA1-84111 detects Amyloid Pre. Protein (Ox-2 Domain) in human and primate samples. PA1-84111 has been successfully used in Western blot and immunoprecipitation applications. The immunogen used to produce PA1-84111 is from a proprietary peptide sequence. |
| General Information |
| This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
(This product is for In Vitro experimental use only.)
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