Anti-FOXO1 Polyclonal Antibody
Printable Datasheet
Synonyms:
FkhR, FoxO1
Entrez Gene ID:
(Rat) 84482
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Rat (Rt) |
| Immunogen: | Synthetic peptide corresponding to residues D(633) N V L P N Q S F P H S V K T(647) of human FOXO1a. |
| Ordering Information | ||||
| Pierce Anti-FOXO1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-804 | 100 µg | $350.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ug of epitope affinity purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide |
| Applications | Dilution |
| Western Blot (WB) | 1:500 |
| Product Specific Information |
| PA1-804 detects FoxO1a. PA1- 804 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~66 kDa protein representing FoxO1a in rat heart and lung protein extracts. The PA1- 804 immunogen is a synthetic peptide corresponding to residues D(633) N V L P N Q S F P H S V K T(647) of human FOXO1a. This sequence is completely conserved in mouse and rat. Fig. 1 shows a Western blot of FoxO1a in rat lung protein extract using PA1-804. |
| General Information |
| FoxO1A belongs to the forkhead family of transcription factors, which are involved in many biological processes and function under the control of the insulin signaling pathway. The mammalian DAF-16-like transcription factors, FoxO1A, FkhRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Dysfunction in FoxO signaling has been linked to insulin resistance and type II diabetes. The FoxO1A gene is mapped to chromosome 13q14. |
(This product is for In Vitro experimental use only.)
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