Part of Thermo Fisher Scientific

Anti-VAMP3 Polyclonal Antibody

Synonyms:
Cellubrevin, Vesicle Associated Membrane Protein 3
Entrez Gene ID:
(Human) 22319
UniProt ID:
P63024
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Sythetic peptide corresponding to residues M(1) S T G V P S G S S A A T G S N R R(18) C of mouse VAMP-3.
Ordering Information
Pierce Anti-VAMP3 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-767A 100 µg $350.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of epitope affinity-purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide.


Applications Dilution
Western Blot (WB) 1:500
Product Specific Information
PA1-767A detects vesicle-associated membrane protein 3 (VAMP-3)/cellubrevin in HeLa samples.

PA1-767A has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~13 kDa protein representing VAMP-3 in HeLa cell lysates.

PA1-767A immunogen is a sythetic peptide corresponding to residues M(1) S T G V P S G S S A A T G S N R R(18) C of mouse VAMP-3. This immunizing peptide (Cat. # PEP-145) is available for use in neutralization and control experiments.

Figure 1 shows a Western blot of VAMP-3 in HeLa cell lysates using PA1-767A.
General Information
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer’s disease, all VAMP isoform levels appear to be significantly reduced.
(This product is for In Vitro experimental use only.)


Learn more about other Thermo Scientific Life Science Research Products
Protein Research Products Cell Culture High Content Screening
Nucleic Acid Technologies PCR Reagents & Plastics RNAi Technologies European Sales

© 2010 Thermo Fisher Scientific Inc.

PO Box 117, Rockford, IL 61105 USA
1-800-874-3723 or 815-968-0747

Trademarks Privacy Statement