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Anti-Vascular Endothelial Growth Factor Polyclonal Antibody

Synonyms:
Vascular endothelial growth factor
Entrez Gene ID:
(Human) 7422
UniProt ID:
P15692
Details
Host / Isotype: Sheep
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Recombinant human VEGF
Ordering Information
Pierce Anti-Vascular Endothelial Growth Factor Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-75502 500 µg $1,148.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 500 µg antibody in 20mM Phosphate, 150mM NaCl, with 0.09% Sodium azide.


Applications Dilution
ELISA (ELISA) Assay Dependent
Product Specific Information
PA1-75502 specifically detects VEGF.

PA1-75502 has been successfully used in ELISA applications.

The PA1-75502 immunogen is Recombinant VEGF.
General Information
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
(This product is for In Vitro experimental use only.)


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