| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Rat (Rt) |
| Immunogen: | Synthetic peptide corresponding to residues from the C-terminal region of rat stargazin. |
| Ordering Information | ||||
| Pierce Anti-Stargazin Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-4709 | 100 ul | $285.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl affinity purified antibody in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Applications | Dilution |
| Western Blot (WB) | 1:1000 |
| Product Specific Information |
| PA1-4709 detects Stargazin from rat samples. PA1-4709 has been successfully used in Western blot procedures. By Western blot, PA1-4709 detects the ~ 36 kDa Stargazin protein. PA1-4709 immunogen is a synthetic peptide corresponding to residues from the C-terminal region of rat stargazin. Figure 1 shows a Western blot of rat synaptic membrane (SPM) showing detection of the ~ 36 kDa stargazin protein. |
| General Information |
| Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors. |
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