Anti-RAB3 Polyclonal Antibody
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Rat (Rt) |
| Immunogen: |
Synthetic peptide corresponding to the N-terminal region of Rab 3 protein. |
|
| Pierce Anti-RAB3 Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| PA1-4691 |
100 µl |
$342.00 |
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 µl of affinity purified antibody in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. |
PA1-4691 dete
PA1-4691 detects Rab 3 protein in rat samples. It is anticipated that the antibody will work in human, mouse, Xenopus, and non-human primates based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
PA1-4691 has been successfully used in Western blotting. By Western blot, this antibody is specific for ~27 kDa Rab 3 protein.
PA1-4691 immunogen is a Peptide corresponding to amino acid residues from the N-terminal region of rat
Rab 3, conjugated to keyhole limpet hemocyanin (KLH).
Figure 1 shows a Western blot of rat cortex lysate showing specific labeling of the ~27 kDa
Rab3 protein. |
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab 3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).
Anti-Rab 3. |
|
No references for this product. |
This product is for In Vitro experimental use only
Printable Datasheet
