Anti-Dopamine beta Hydroxylase Polyclonal Antibody
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Human (Hu) Non-human primate (Nhp) |
| Immunogen: |
Peptide from the N-terminus region of human Dopamine-Hydroxylase (DBH), conjugated to KLH. |
|
| Pierce Anti-Dopamine beta Hydroxylase Polyclonal Antibody |
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| Product Number |
Pkg Size |
Price |
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| PA1-4655 |
100 µl |
$285.00 |
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| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 ul of affinity purified IgG in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. |
PA1-4655 detects Dopamine beta-Hydroxylase (N-terminus) in human and non-human primate samples.
PA1-4655 has been successfully used in Western blotting. It is specific for the ~75 kDa DBH protein in Western blots of human adrenal medulla. It also recognizes DBH in monkey tissues.
PA1-4655 immunogen is a peptide from the N-terminus region of human Dopamine '-Hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH). The sequence of the immunogen is identical in human and non-human primate.
Figure 1 shows a Western blot of human adrenal medulla. As shown in the autoradiograph, the antibody is specific for the ~75 kDa DBH protein. |
DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic
neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001). |
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No references for this product. |
This product is for In Vitro experimental use only
Printable Datasheet
