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Anti-STIM1 Polyclonal Antibody

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Synonyms:
D11S4896E, GOK
Entrez Gene ID:
(Human) 6786
UniProt ID:
Q13586
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt) Canine (Ca) Bovine (Bv)
Immunogen: Synthetic peptide made to a C-terminal region with residues 600-685 of the human protein.[Uniprot#Q13586]
Ordering Information
Pierce Anti-STIM1 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-46217 100 µl $342.00


Storage: 4º C
Form: 100 µl peptide affinity purified Rabbit antisera (1 mg/ml) in PBS, 30% glycerol with 0.1% sodium azide.


Applications Dilution
Immunocytochemistry (ICC) Assay Dependent
Immunofluorescence (IF) Assay Dependent
Western Blot (WB) 0.5-2.0 µg/ml
Product Specific Information
The PA1-46217 antibody reacts with STIM1 in human, mouse, rat, bovine, and canine samples.PA1-46217 has a 79% sequence identity with Xenopus.

PA1-46217 has been successfully used in Western Blot applications. By Western blot, this antibody detects a ~77 kDa band, representing the STIM-1 protien. Two other non-specific bands of lower MW may also appear.

The PA1-46217 antibody was raised against a synthetic peptide made to a C-terminal region (within residues 600-685) of the human protein. [Uniprot# Q13586].

Store at 4ºC short term. Aliquot and store at -20ºC long term. Avoid Freeze/Thaw Cycles.
General Information
Stromal interaction molecule 1 plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. It acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, it translocates from the endoplasmic recticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit.
Western Blot with anti-STIM1 Polyclonal Antibody (PA1-46217)
(This product is for In Vitro experimental use only.)


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