| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide: L(521) K E A I L K K K I G K P E I K I L H(539) |
| Ordering Information | ||||
| Pierce Anti-DPP10 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-4385 | 100 µg | $319.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of epitope affinity purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1:500 |
| Product Specific Information |
| PA1-4385 detects DPP10 in human samples. PA1-4385 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~75 kDa protein representing DPP10. Oligermization and differential glycosylation produces other bands as observed with other DPP family members. PA1-4385 immunizing peptide corresponds to amino acid residues 521-539 of human DPP10. Figure 1 shows a Western blot of human DPP10 protein expressed in transfected CHO cells using PA1-4385. |
| General Information |
| A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma. |
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Box 117, Rockford, IL 61105 USA |
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