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Anti-DPP10 Polyclonal Antibody

Synonyms:
Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPL2, Dipeptidyl peptidase IV-related protein 3, DPRP-3
Entrez Gene ID:
(Human) 57628
UniProt ID:
Q8N608
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide: L(521) K E A I L K K K I G K P E I K I L H(539)
Ordering Information
Pierce Anti-DPP10 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-4385 100 µg $319.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of epitope affinity purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide.


Applications Dilution
Western Blot (WB) 1:500
Product Specific Information
PA1-4385 detects DPP10 in human samples.

PA1-4385 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~75 kDa protein representing DPP10. Oligermization and differential glycosylation produces other bands as observed with other DPP family members.

PA1-4385 immunizing peptide corresponds to amino acid residues 521-539 of human DPP10.

Figure 1 shows a Western blot of human DPP10 protein expressed in transfected CHO cells using PA1-4385.
General Information
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
(This product is for In Vitro experimental use only.)


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