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Anti-Olfactomedin 4 Polyclonal Antibody

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Details
Host / Isotype: Rabbit / Ig
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu) Non-human primate (Nhp)
Immunogen: Synthetic peptide corresponding to residues 400-450 of human Olfactomedin 4.
Applications Dilution
Western Blot (WB) 0.5-2 µg/ml
Ordering Information
Pierce Anti-Olfactomedin 4 Polyclonal Antibody
Product Number Pkg Size Price


PA1-41570 100 µg $285.00
Storage: -20°C
Form: 100 µg antibody in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide.


Product Specific Information General Information
PA1-41570 detects Olfactomedin 4 in non-human primate, human samples.

PA1-41570 has been successfully used in Western blot applications.

The PA1-41570 immunogen is a synthetic peptide corresponding to residues 400-450 of human Olfactomedin 4.
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase.  Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
References:

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