| Details | |
| Host / Isotype: | Rabbit / Ig |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Non-human primate (Nhp) |
| Immunogen: | Synthetic peptide corresponding to residues 400-450 of human Olfactomedin 4. |
| Ordering Information | ||||
| Pierce Anti-Olfactomedin 4 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-41570 | 100 µg | $285.00 | ||
| Storage: | -20°C |
| Form: | 100 µg antibody in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 0.5-2 µg/ml |
| Product Specific Information |
| PA1-41570 detects Olfactomedin 4 in non-human primate, human samples. PA1-41570 has been successfully used in Western blot applications. The PA1-41570 immunogen is a synthetic peptide corresponding to residues 400-450 of human Olfactomedin 4. |
| General Information |
| OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion. |
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Box 117, Rockford, IL 61105 USA |
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