| Details | |
| Host / Isotype: | Rabbit / Ig |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Non-human primate (Nhp) Xenopus laevis (Xl) |
| Immunogen: | Synthetic peptide corresponding to residues 400-450 of human PACSIN 2. |
| Ordering Information | ||||
| Pierce Anti-PACSIN 2 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-41564 | 100 µg | $342.00 | ||
| Storage: | -20°C |
| Form: | 100 µg antibody (0.5 mg/ml) in PBS containing 0.2% gelatin and 0.05% sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/ml |
| Western Blot (WB) | 0.02-1 µg/ml |
| Product Specific Information |
| PA1-41564 detects PACSIN 2 in non-human primate, human and Xenopus laevis samples. PA1-41564 is predicted to react with murine, rat, canine, bovine, and chicken. PA1-41564 has been successfully used in Western blot applications. A suggested positive control is human, mouse and rat brain lysate. The PA1-41564 immunogen is a synthetic peptide corresponding to residues 400-450 of human PACSIN 2. |
| General Information |
| PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling. |
|
|||||||||||||
PO
Box 117, Rockford, IL 61105 USA |
|