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Anti-PACSIN 2 Polyclonal Antibody

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Synonyms:
RP3-437M21.1, SDPII
Entrez Gene ID:
(Human) 11252
UniProt ID:
Q9UNF0
Details
Host / Isotype: Rabbit / Ig
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Non-human primate (Nhp) Xenopus laevis (Xl)
Immunogen: Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
Ordering Information
Pierce Anti-PACSIN 2 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-41564 100 µg $342.00


Storage: -20°C
Form: 100 µg antibody (0.5 mg/ml) in PBS containing 0.2% gelatin and 0.05% sodium azide.


Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 10 µg/ml
Western Blot (WB) 0.02-1 µg/ml
Product Specific Information
PA1-41564 detects PACSIN 2 in non-human primate, human and Xenopus laevis samples. PA1-41564 is predicted to react with murine, rat, canine, bovine, and chicken.

PA1-41564 has been successfully used in Western blot applications. A suggested positive control is human, mouse and rat brain lysate.

The PA1-41564 immunogen is a synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
General Information
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
Immunohistochemistry with anti-PACSIN 2 Polyclonal Antibody (PA1-41564)
Western Blot with anti-PACSIN 2 Polyclonal Antibody (PA1-41564)
(This product is for In Vitro experimental use only.)


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