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Anti-PACSIN 2 Polyclonal Antibody

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Details
Host / Isotype: Rabbit / Ig
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu) Non-human primate (Nhp) Xenopus laevis (Xl)
Immunogen: Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
Applications Dilution
Western Blot (WB) 0.02-1 µg/ml
Ordering Information
Pierce Anti-PACSIN 2 Polyclonal Antibody
Product Number Pkg Size Price


PA1-41564 100 µg $342.00
Storage: -20°C
Form: 100 µg antibody in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide.


Product Specific Information General Information
PA1-41564 detects PACSIN 2 in non-human primate, human and Xenopus laevis samples.

PA1-41564 has been successfully used in Western blot applications.

The PA1-41564 immunogen is a synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
References:

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