| Details | |
| Host / Isotype: | Rabbit / Ig |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to residues 300-350 of human SSTR5. |
| Ordering Information | ||||
| Pierce Anti-Somatostatin Receptor 5 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-41496 | 100 µg | $285.00 | ||
| Storage: | -20°C |
| Form: | 100 µg antibody in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 0.1-1 µg/ml |
| Product Specific Information |
| PA1-41496 detects Somatostatin receptor 5 in human samples. PA1-41496 has been successfully used in Western blot applications. The PA1-41496 immunogen is a synthetic peptide corresponding to residues 300-350 of human SSTR5. |
| General Information |
| Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly. |
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