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Anti-PTCH Polyclonal Antibody

Printable Datasheet

Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH.
Applications Dilution
Western Blot (WB) 1:500
Ordering Information
Pierce Anti-PTCH Polyclonal Antibody
Product Number Pkg Size Price


PA1-4134 100 µg $317.00
Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of epitope affinity purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide.


Product Specific Information General Information
PA1-4134 detects Patched (PTCH) in human samples.

PA1-4134 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH in fetal brain lysate.

The PA1-4134 immunogen is a synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH. This sequence is 100% conserved in mouse, rat, and chicken PTCH.

Figure 1 illustrates Western blot detection of human PTCH1 from human fetal brain lysate using PA1-4134.
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.
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References:

No references for this product.

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