Anti-PTCH Polyclonal Antibody
Printable Datasheet
Synonyms:
Patched, PTC1, PTC, Protein patched homolog 1
Entrez Gene ID:
(Human) 5727
UniProt ID:
Q13635
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) Chicken (Ck) |
| Immunogen: | Synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH. |
| Ordering Information | ||||
| Pierce Anti-PTCH Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-4134 | 100 µg | $317.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ug of epitope affinity purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1:500-1:1000 |
| Product Specific Information |
| PA1-4134 detects Patched (PTCH) in human samples. PA1-4134 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH in fetal brain lysate. The PA1-4134 immunogen is a synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH. This sequence is 100% conserved in human, rat, and chicken PTCH, and is expected to cross react with these samples. Figure 1 illustrates Western blot detection of human PTCH1 from human fetal brain lysate using PA1-4134. |
| General Information |
| Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. |
(This product is for In Vitro experimental use only.)
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