| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) Canine (Ca) |
| Immunogen: | Synthetic peptide corresponding to residues 800-850 of human NRIP. |
| Ordering Information | ||||
| Pierce Anti-Nuclear Rec. Interacting Protein Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-41255 | 100 µg | $342.00 | ||
| Storage: | -20°C |
| Form: | 100 µg antibody in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1-3 µg/ml |
| Product Specific Information |
| PA1-41255 detects Nuclear Receptor Interacting Protein in canine, human, rat and murine samples. PA1-41255 has been successfully used in Western blot applications. The PA1-41255 immunogen is a synthetic peptide corresponding to residues 800-850 of human NRIP. |
| General Information |
| NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland. |
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Box 117, Rockford, IL 61105 USA |
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