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ACTIVIN RECEPTOR IA ANTIBODIES > ACTIVIN RECEPTOR IA POLYCLONAL ANTIBODY PA1-41185
Anti-Activin Receptor IA Polyclonal Antibody
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Synonyms:
ACVR1
Entrez Gene ID:
(Human) 90, (Murine) 11477, (Rat) 79558
UniProt ID:
Q04771
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: | Synthetic peptide corresponding to residues 475-525 of human ACVR1. |
| Ordering Information | ||||
| Pierce Anti-Activin Receptor IA Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-41185 | 100 µg | $342.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of Protein G purified antibody in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 3-5 µg/ml |
| Product Specific Information |
| PA1-41185 detects Activin Receptor Type 1A in human, rat and murine samples. PA1-41185 has been successfully used in Western blot applications. By Western blot, this antibody detects a ~54 kDa band representing Activin Receptor Type IA. Additional non-specific bands at ~14 and 27 kDa may also be detected in human kidney samples. The PA1-41185 immunogen is a synthetic peptide corresponding to residues 475-525 of human ACVR1. |
| General Information |
| Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. |
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Western Blot with anti-Activin Receptor IA Polyclonal Antibody (PA1-41185)
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(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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