| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant protein containing human MMP-3 residues 251-478. |
| Ordering Information | ||||
| Pierce Anti-MMP3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-38175 | 7 ml | $268.00 | ||
| Storage: | 4ยบ C |
| Form: | 7 ml of prediluted antibody. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay Dependent |
| Product Specific Information |
| PA1-38175 detects MMP-3 from human samples. PA1-38175 has been successfully used in immunohistochemistry (paraffin) applications. The PA1-38175 immunogen is a recombinant protein containing human MMP-3 residues 251-478. |
| General Information |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive pre-proteins which are activated when cleaved by extracellular proteinases. It is thought that this protein is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. |
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Box 117, Rockford, IL 61105 USA |
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