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Anti-MMP3 Polyclonal Antibody

Synonyms:
Stromelysin-1
Entrez Gene ID:
(Human) 4314
UniProt ID:
P08254
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Recombinant protein containing human MMP-3 residues 251-478.
Ordering Information
Pierce Anti-MMP3 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-38175 7 ml $268.00


Storage: 4ยบ C
Form: 7 ml of prediluted antibody.


Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) Assay Dependent
Product Specific Information
PA1-38175 detects MMP-3 from human samples.

PA1-38175 has been successfully used in immunohistochemistry (paraffin) applications.

The PA1-38175 immunogen is a recombinant protein containing human MMP-3 residues 251-478.
General Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive pre-proteins which are activated when cleaved by extracellular proteinases. It is thought that this protein is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema.
(This product is for In Vitro experimental use only.)


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