| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant, full length human Galectin-3 protein. |
| Ordering Information | ||||
| Pierce Anti-Galectin 3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-37737 | 200 µg | $411.00 | (DISCONTINUED) | |
| Storage: | 4º C |
| Form: | 200 µg of epitope affinity purified IgG (0.2 mg/ml) in PBS containing sodium azide and BSA. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:30 |
| Product Specific Information |
| PA1-37737 detects Galectin-3 from human samples. PA1-37737 has been successfully used in immunohistochemistry (paraffin) applications. The PA1-37737 immunogen is recombinant, full length human Galectin-3 protein. |
| General Information |
| The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control. |
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Box 117, Rockford, IL 61105 USA |
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