Anti-CD105 Polyclonal Antibody
Printable Datasheet
Synonyms:
ENG, END, HHT1, ORW, ORW1, Endoglin
Entrez Gene ID:
(Human) 2022
UniProt ID:
P17813
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant protein containing residues 26-176 of human CD105. |
| Ordering Information | ||||
| Pierce Anti-CD105 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-37371 | 7 ml | $157.00 | ||
| Storage: | 4ยบ C, DO NOT FREEZE! |
| Form: | 7 ml of prediluted antibody in a 50 mM Tris/1% BSA buffer, pH 7.6, with 0.1% sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay Dependent |
| Product Specific Information |
| PA1-37371 detects CD105 from human samples. PA1-37371 has been successfully used in immunohistochemistry (paraffin) applications. Antigen retrieval requires boiling tissue sections in 10 mM sodium citrate, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 minutes. The PA1-37371 immunogen is a recombinant protein containing residues 26-176 of human CD105. |
| General Information |
| CD105 or endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-beta1 and beta3 with high affinity but not TGF-beta2. |
(This product is for In Vitro experimental use only.)
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