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Anti-alpha PAK Polyclonal Antibody

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Synonyms:
PAK65, PAKgamma
Entrez Gene ID:
(Human) 5062, (Murine) 224105, (Rat) 29432
UniProt ID:
Q13177
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: Synthetic peptide corresponding to the amino acids 525-545 of rat alpha PAK.
Ordering Information
Pierce Anti-alpha PAK Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-37067 1 ml $508.00


Storage: 4º C
Form: 200 µg of epitope affinity purified IgG (0.2 mg/ml) in 10 mM PBS, pH 7.4, containing 0.1% sodium azide and 1% BSA.


Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 1:50
Western Blot (WB) Assay Dependent
Product Specific Information
PA1-37067 detects alpha PAK (molecular weight 65 kDa) from human, mouse, and rat samples.

PA1-37067 has been successfully used in immunohistochemistry (paraffin) and Western blot applications. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at room temperature for 20 minutes.

The PA1-37067 immunogen is a synthetic peptide corresponding to the amino acids 525-545 of rat alpha PAK.
General Information
Alpha PAK p68, beta PAK p65 and gamma PAK p62 are three isoforms of serine/threonine kinases. These three isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation.
Immunohistochemistry with anti-alpha PAK Polyclonal Antibody (PA1-37067)
(This product is for In Vitro experimental use only.)


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