Anti-CYP3A4 Polyclonal Antibody
Printable Datasheet
Synonyms:
CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1
Entrez Gene ID:
(Human) 1576
UniProt ID:
P08684
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Purified human CYP3A4 expressed in E.Coli |
| Ordering Information | ||||
| Pierce Anti-CYP3A4 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-33095 | 50 µl | $463.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µl of unpurified liquid antibody with 0.09% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | Assay dependent |
| Product Specific Information |
| PA1-33095 detects CYP3A4 from human samples. PA1-33095 has been successfully used in Western blot applications. The PA1-33095 immunogen is: Purified human CYP3A4 expressed in E.Coli |
| General Information |
| This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. |
(This product is for In Vitro experimental use only.)
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