| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) |
| Immunogen: | Synthetic peptide corresponding to an internal region of human ABCG1 (between residues 300-400). |
| Ordering Information | ||||
| Pierce Anti-ABCG1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-32403 | 100 µl | $440.00 | ||
| Storage: | 4º C |
| Form: | 100 µl of purified antibody (1 mg/ml) in Tris-citrate/phosphate, pH 7-8 with 0.1% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1:2500 |
| Product Specific Information |
| PA1-32403 detects ABCG1 from human and mouse samples. There is 100/100% identity/homology of the immunogen used for this production and the human protein sequence. There is 84/89% for mouse and 78/88% for rat. PA1-32403 has been successfully used in Western blot applications. The PA1-32403 immunogen is synthetic peptide corresponding to an internal region of human ABCG1 (between residues 300-400). |
| General Information |
| ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1. |
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Box 117, Rockford, IL 61105 USA |
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