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Anti-von Willebrand Factor Polyclonal Antibody

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Synonyms:
F8VWF, vWF, VWD, Von Willebrand antigen II
Entrez Gene ID:
(Human) 7450
UniProt ID:
P04275
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Full length, native protein purified from human plasma.
Ordering Information
Pierce Anti-von Willebrand Factor Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-26828 100 µl $356.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µl of IgG fraction antibody (7.8 mg/ml) in 0.01 M PBS with 15 mM sodium azide; pH 7.4.


Applications Dilution
Immunohistochemistry (Frozen) (IHC (F)) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 1:800
Product Specific Information
PA1-26828 detects Von Willebrand Factor from human samples. PA1-26828 will not react with chicken.

PA1-26828 has been successfully used in immunofluorescence and immunohistochemistry (paraffin and frozen) procedures.

The PA1-26828 immunogen is full length, native protein purified from human plasma.

Figure 1 illustrates a confocal extended focus photograph of Von Willebrand Factor staining (red) and non-specific nuclear counterstain (green) in the adult mouse olfactory bulb. This picture shows a single major vessel within the glomerular layer of the olfactory bulb.

Figure 2 illustrates immunohistochemical localization of Von Willebrand Factor in BCG infected guinea pig lung tissue.
General Information
Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis.
Immunofluorescence with anti-von Willebrand Factor Polyclonal Antibody (PA1-26828)
Immunohistochemistry with anti-von Willebrand Factor Polyclonal Antibody (PA1-26828)
(This product is for In Vitro experimental use only.)


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