| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Ordering Information | ||||
| Pierce Anti-DAP3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-26481 | 50 µg | $354.00 | ||
| Storage: | -80º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µg of immunogen affinity purified antibody (0.2 mg/ml) in PBS, 50% glycerol, 1% BSA with 0.02% sodium azide; pH 7.2. |
| Applications | Dilution |
| Western Blot (WB) | 1 - 2 µg/ml |
| Product Specific Information |
| PA1-26481 detects DAP3 from human samples. PA1-26481 has been successfully used in Western blot procedures. |
| General Information |
| Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. |
|
|||||||||||||
PO
Box 117, Rockford, IL 61105 USA |
|