Anti-MMP2 Polyclonal Antibody
Printable Datasheet
Synonyms:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Entrez Gene ID:
(Human) 4313
UniProt ID:
P08253
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Purified, full length, native human MMP-2. |
| Ordering Information | ||||
| Pierce Anti-MMP2 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-25203 | 25 µg | $314.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 25 µg of IgG fraction antibody (1 mg/ml) in 0.01M PBS, 50% glycerol with 0.05% sodium azide; pH 7.4. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Immunohistochemistry (IHC) | Assay Dependent |
| Western Blot (WB) | 1:5,000 |
| Product Specific Information |
| PA1-25203 detects MMP-2 from human samples. PA1-25203 has been successfully used in immunohistochemistry, and Western blot procedures. The PA1-25203 immunogen is purified, full length, native human MMP-2. |
| General Information |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
(This product is for In Vitro experimental use only.)
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