| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant human XRCC1 |
| Ordering Information | ||||
| Pierce Anti-XRCC1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-23302 | 50 µl | $440.00 | ||
| Storage: | -80º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µl of Rabbit Polyclonal Antiserum (1 mg/ml) antibody in PBS, pH 7.4. No preservatives. |
| Applications | Dilution |
| ELISA (ELISA) | Assay dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay dependent |
| Immunoprecipitation (IP) | Assay dependent |
| Western Blot (WB) | Assay dependent |
| Product Specific Information |
| PA1-23302 detects XRCC1 in Human samples. PA1-23302 has been successfully used in ELISA, Immunohistochemistry (Frozen), Immunoprecipitation and Western Blot procedures. PA1-23302 immunogen corresponds to Recombinant human XRCC1. |
| General Information |
| XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha. |
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Box 117, Rockford, IL 61105 USA |
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