Anti-Dab1 Polyclonal Antibody
Printable Datasheet
Synonyms:
RP23-356E21.1, AI956902, C630028C02Rik, scm, scr, scrambler, yot
Entrez Gene ID:
(Murine) 13131
UniProt ID:
P97318
| Details | |
| Host / Isotype: | Goat / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Murine (Ms) |
| Immunogen: | Recognizes Dab1 of 48 kDa, corresponding to amino acids 399-555 of mouse Dab1 GST fusion protein. |
| Ordering Information | ||||
| Pierce Anti-Dab1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-21178 | 125 µg | $393.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 125 µg of Protein G purified (1 mg/ml) antibody in 0.08% Sodium Azide; PBS |
| Applications | Dilution |
| Immunoprecipitation (IP) | 5 µg/ml. |
| Western Blot (WB) | 1 µg/ml. |
| Product Specific Information |
| PA1-21178 detects Dab1 in Mouse samples. PA1-21178 has been successfully used in Immunoprecipitation and Western Blot procedures. PA1-21178 immunogen corresponds to Recognizes Dab1 of 48 kDa, corresponding to amino acids 399-555 of mouse Dab1 GST fusion protein.. |
| General Information |
| Disruption of Dab1 results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. DAB1 acts downstream of reelin in a signalling pathway. |
(This product is for In Vitro experimental use only.)
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