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MGLUR 2/3 ANTIBODIES > MGLUR 2/3 POLYCLONAL ANTIBODY PA1-21034
Anti-mGluR 2/3 Polyclonal Antibody
Printable Datasheet| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) Non-human primate (Nhp) Amphibian (Am) |
| Immunogen: | Synthetic peptide (Human) (C-terminal). |
| Ordering Information | ||||
| Pierce Anti-mGluR 2/3 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-21034 | 7 ml | $396.00 | ||
| Storage: | 4ยบ C |
| Form: | 7 ml of prediluted antibody in PBS, pH 7.4 containing 1% BSA and 0.1% sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | Neat |
| Product Specific Information |
| PA1-21034 detects Metabotropic Glutamate Receptor 2 & 3 in Human, Mouse, Rat, Amphibian and Non-human primate samples. PA1-21034 has been successfully used in Immunohistochemistry (Paraffin) procedures. PA1-21034 immunogen corresponds to synthetic peptide (Human) (C-terminal). |
| General Information |
| L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. |
(This product is for In Vitro experimental use only.)
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